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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin-interacting protein 1

UniprotKB/SwissProt ID: Q9VU68 (Q9VU68)

Gene Name: flr

Organism: Drosophila melanogaster (Fruit fly)

Function: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:17565945). Together with GMF, promotes Arp2/3-nucleated actin filament array disassembly (PubMed:25308079). Essential for organismal and cell viability (PubMed:17565945). Required for the development of normal wing cell planar polarity (PubMed:17565945). In egg chambers and together with GMF, plays an important role in directional migration of border cell clusters (PubMed:25308079)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt