Protein Name:
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
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UniprotKB/SwissProt ID: Q9VSA3 (Q9VSA3)
Gene Name:
Mcad
Organism: Drosophila melanogaster (Fruit fly)
Function: Medium-chain specific acyl-CoA dehydrogenase that catalyzes the first step of mitochondrial fatty acid beta-oxidation, an aerobic process that breaks down fatty acids into acetyl-CoA and allows the production of energy from fats (PubMed:29563254). The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). May contribute to Pink1-mediated regulation of fatty acid and amino acid metabolism, through a mechanism that is independent of its acyl-CoA dehydrogenase activity (PubMed:29563254)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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