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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 4'-phosphopantetheine phosphatase

UniprotKB/SwissProt ID: Q9VMU2 (Q9VMU2)

Gene Name: Dmel\CG5828

Organism: Drosophila melanogaster (Fruit fly)

Function: Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036075 ARMT-1-like_metal-bd_sf
IPR002791 ARMT1-like_metal-bd
IPR016949 At2g17340
IPR035073 At2g17340_3_helix_bundle
IPR004567 Type_II_PanK