Protein Name:
Zinc finger CCCH domain-containing protein 4
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UniprotKB/SwissProt ID: Q9UPT8 (Q9UPT8)
Gene Name:
ZC3H4
Organism: Homo sapiens (Human)
Function: RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) (PubMed:33767452, PubMed:33913806). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein (PubMed:33767452, PubMed:33913806). Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome (PubMed:33767452, PubMed:33913806). The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs (PubMed:33767452)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Chromosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UPT8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1302 |
KGFDPTASPF C Q--------- |
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