Protein Name:
Trinucleotide repeat-containing gene 6B protein
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UniprotKB/SwissProt ID: Q9UPQ9 (Q9UPQ9)
Gene Name:
TNRC6B
Organism: Homo sapiens (Human)
Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs) (PubMed:16289642, PubMed:19167051, PubMed:19304925, PubMed:32354837). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins (PubMed:16289642, PubMed:19167051, PubMed:19304925, PubMed:32354837). As scaffolding protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes (PubMed:21981923)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, P-body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UPQ9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
202 |
VDGSDMEEWP C IASKDTESSS |
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| 2 |
254 |
QCQSASSGNE C NLGVWKSDPK |
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