Protein Name:
Zinc finger MIZ domain-containing protein 1
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UniprotKB/SwissProt ID: Q9ULJ6 (Q9ULJ6)
Gene Name:
ZMIZ1
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional coactivator. Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation (PubMed:14609956, PubMed:26522984). Also functions as a transcriptional coactivator in the TGF-beta signaling pathway by increasing the activity of the SMAD3/SMAD4 transcriptional complex (PubMed:16777850). Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development (By similarity). Involved in the regulation of postmitotic positioning of pyramidal neurons in the developing cerebral cortex (PubMed:30639322)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleoplasm. Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9ULJ6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
81 |
LDLGYRLLAV C AANRDKFTPK |
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