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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein WWC3

UniprotKB/SwissProt ID: Q9ULE0 (Q9ULE0)

Gene Name: WWC3

Organism: Homo sapiens (Human)

Function: Regulator of the Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway. Enhances phosphorylation of LATS1 and YAP1 and negatively regulates cell proliferation and organ growth due to a suppression of the transcriptional activity of YAP1, the major effector of the Hippo pathway

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR037771 C2_WWC
IPR001202 WW_dom
IPR036020 WW_dom_sf
IPR051105 WWC/KIBRA_Hippo_Reg