Protein Name:
Microtubule-associated tumor suppressor 1
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UniprotKB/SwissProt ID: Q9ULD2 (Q9ULD2)
Gene Name:
MTUS1
Organism: Homo sapiens (Human)
Function: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Golgi apparatus. Cell membrane. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR051293
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MTUS1/CCDC69 |
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The S-nitrosylation sites of Q9ULD2
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
427 |
DMVISTDKTM C MSTPVLEPTK |
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| 2 |
475 |
PDSKEAPVNL C KPSLGKSTIK |
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| 3 |
492 |
STIKTNTPIG C KVRKTEIISY |
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| 4 |
625 |
VDKASSSNSA C ETGSVSALFQ |
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| 5 |
717 |
SGRNISKPDS C GLRQIAAPKA |
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| 6 |
975 |
RGELVTASTT C EKLEKARNEL |
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