\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Protein argonaute-1

UniprotKB/SwissProt ID: Q9UL18 (Q9UL18)

Gene Name: AGO1

Organism: Homo sapiens (Human)

Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, P-body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR014811 ArgoL1
IPR032472 ArgoL2
IPR032473 Argonaute_Mid_dom
IPR032474 Argonaute_N
IPR003100 PAZ_dom
IPR036085 PAZ_dom_sf
IPR003165 Piwi
IPR045246 Piwi_ago-like
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

The S-nitrosylation sites of Q9UL18

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 342 QKHTYLPLEV C NIVAGQRCIK