Protein Name:
Nuclear pore complex protein Nup50
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UniprotKB/SwissProt ID: Q9UKX7 (Q9UKX7)
Gene Name:
NUP50
Organism: Homo sapiens (Human)
Function: Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008). Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nuclear pore complex. Nucleus membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UKX7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
151 |
SSSGLASSKA C VGNAYHKQLA |
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| 2 |
165 |
AYHKQLAALN C SVRDWIVKHV |
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| 3 |
181 |
IVKHVNTNPL C DLTPIFKDYE |
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| 4 |
333 |
EGQAEGDSGE C KGGDEEENDE |
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| 5 |
416 |
LNVLIPPNMP C TRTGKNNVLI |
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