Protein Name:
General transcription factor 3C polypeptide 4
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UniprotKB/SwissProt ID: Q9UKN8 (Q9UKN8)
Gene Name:
GTF3C4
Organism: Homo sapiens (Human)
Function: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin (PubMed:10523658). Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3 (PubMed:10523658). May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F (PubMed:10523658). May be localized close to the A box (PubMed:10523658)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UKN8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
116 |
RTSVPAPLNS C LLKVGSKTEV |
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| 2 |
257 |
TPVRMEWSGI C TTQQVKHNNE |
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| 3 |
388 |
PLYHPYQKCS C SLVVAARGSY |
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| 4 |
713 |
ENTSIPTRGL C NFLMSDEEYD |
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| 5 |
814 |
DWIKRLLQSP C PFCDSPVF-- |
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