Protein Name:
F-box/LRR-repeat protein 4
|
UniprotKB/SwissProt ID: Q9UKA2 (Q9UKA2)
Gene Name:
FBXL4
Organism: Homo sapiens (Human)
Function: Substrate-recognition component of the mitochondria-localized SCF-FBXL4 ubiquitin E3 ligase complex that plays a role in the restriction of mitophagy by controlling the degradation of BNIP3 and NIX mitophagy receptors (PubMed:36896912, PubMed:38992176). Rescues also mitochondrial injury through reverting hyperactivation of DRP1-mediated mitochondrial fission (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Mitochondrion outer membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
