Protein Name:
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial
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UniprotKB/SwissProt ID: Q9UJS0 (Q9UJS0)
Gene Name:
SLC25A13
Organism: Homo sapiens (Human)
Function: Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:38945283). Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton (PubMed:11566871). Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (PubMed:11566871). Lacks transport activity towards gamma-aminobutyric acid (GABA) (PubMed:38945283)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UJS0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
377 |
GELMYKNSFD C FKKVLRYEGF |
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| 2 |
503 |
DIPFSAIYFP C YAHVKASFAN |
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| 3 |
565 |
GQTTYSGVID C FRKILREEGP |
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