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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cardiolipin synthase (CMP-forming)

UniprotKB/SwissProt ID: Q9UJA2 (Q9UJA2)

Gene Name: CRLS1

Organism: Homo sapiens (Human)

Function: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG) (PubMed:16547353, PubMed:16678169, PubMed:16716149, PubMed:35147173). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions (PubMed:35147173)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050324 CDP-alcohol_PTase-I
IPR000462 CDP-OH_P_trans
IPR043130 CDP-OH_PTrfase_TM_dom

The S-nitrosylation sites of Q9UJA2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 230 PRTLAKYFNP C YATARLKPTF