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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rab5 GDP/GTP exchange factor

UniprotKB/SwissProt ID: Q9UJ41 (Q9UJ41)

Gene Name: RABGEF1

Organism: Homo sapiens (Human)

Function: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Early endosome. Recycling endosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR041545 DUF5601
IPR003123 VPS9
IPR045046 Vps9-like
IPR037191 VPS9_dom_sf
IPR002653 Znf_A20

The S-nitrosylation sites of Q9UJ41

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 181 RDLSIEEQSE C AQDFYHNVAE   
2 225 IMTRLYKYVF C PETTDDEKKD