UniprotKB/SwissProt ID: Q9UHX3 (Q9UHX3)
Gene Name:
ADGRE2
Organism: Homo sapiens (Human)
Function: Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell projection, ruffle membrane
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