Protein Name:
DnaJ homolog subfamily B member 11
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UniprotKB/SwissProt ID: Q9UBS4 (Q9UBS4)
Gene Name:
DNAJB11
Organism: Homo sapiens (Human)
Function: As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins (PubMed:10827079, PubMed:15525676, PubMed:29706351). Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed (PubMed:15525676). May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity (PubMed:10827079). It is necessary for maturation and correct trafficking of PKD1 (PubMed:29706351)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum lumen
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UBS4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
196 |
QMTQEVVCDE C PNVKLVNEER |
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