Protein Name:
SUMO-activating enzyme subunit 1
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UniprotKB/SwissProt ID: Q9UBE0 (Q9UBE0)
Gene Name:
SAE1
Organism: Homo sapiens (Human)
Function: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9UBE0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
214 |
TTMVKKKVVF C PVKEALEVDW |
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| 2 |
295 |
DLLPEDFVRY C FSEMAPVCAV |
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| 3 |
342 |
DGMKGNGIVE C LGPK------ |
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