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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Origin recognition complex subunit 3

UniprotKB/SwissProt ID: Q9UBD5 (Q9UBD5)

Gene Name: ORC3

Organism: Homo sapiens (Human)

Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020795 ORC3
IPR045663 ORC3_ins
IPR045667 ORC3_N
IPR040855 ORC_WH_C

The S-nitrosylation sites of Q9UBD5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 363 RRINFLSNNQ C ENIRRLPSFR   
2 561 LRENVVNFID C LVREYLLPPE   
3 630 GCIPNIAPDI C IAYKLHLECS