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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Epidermal growth factor receptor substrate 15-like 1

UniprotKB/SwissProt ID: Q9UBC2 (Q9UBC2)

Gene Name: EPS15L1

Organism: Homo sapiens (Human)

Function: Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Nucleus. Membrane, coated pit

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR000261 EH_dom
IPR018159 Spectrin/alpha-actinin