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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Adenylate kinase 2

UniprotKB/SwissProt ID: Q9U915 (Q9U915)

Gene Name: Ak2

Organism: Drosophila melanogaster (Fruit fly)

Function: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (By similarity) (PubMed:19416704). Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways (By similarity). Essential for viability (PubMed:19416704)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Mitochondrion intermembrane space

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006259 Adenyl_kin_sub
IPR000850 Adenylat/UMP-CMP_kin
IPR033690 Adenylat_kinase_CS
IPR007862 Adenylate_kinase_lid-dom
IPR028587 AK2
IPR027417 P-loop_NTPase