Protein Name:
Regulatory protein NPR2
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UniprotKB/SwissProt ID: Q9SZI3 (Q9SZI3)
Gene Name:
NPR2
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Transcription cofactor that represses gene expression in the absence of salicylic acid (SA), when attached to negative cis-elements (W-box) with WRKY transcription factors, but stimulates gene expression upon activation by SA, when sumoylated and attached to positive cis-elements (as-1) with TGA transcription factors, thus confering immunity through a series of gene regulations ending in a significant increase in antimicrobial and defense genes expression (By similarity). May be involved in regulating basal defense responses against pathogens, and may be involved in crosstalk between SA- and JA-dependent signaling pathways (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nuclear body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9SZI3
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
155 |
GASACVDDDC C HVACRSKVDF |
CCCEEECEEE E CCCCEEECCC |
3.58% |
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