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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: L-galactono-1,4-lactone dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: Q9SU56 (Q9SU56)

Gene Name: GLDH

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Involved in the biosynthesis of ascorbate (PubMed:18190525). Catalyzes the final step of ascorbate biosynthesis (PubMed:18190525). Uses L-galactono-1,4-lactone and L-gulono-1,4-lactone as substrates, but not D-galactono-1,4-lactone, D-gulono-1,4-lactone, L-mannono-1,4-lactone or D-galactonic acid (PubMed:18190525). Also active with phenazine methosulfate and 1,4-benzoquinone as electron acceptors (PubMed:18190525). Involved in the regulation of the accumulation of the mitochondrial respiratory complex I (PubMed:18799460, PubMed:33060577). Structural part of one of the plant-specific mitochondrial complex I assembly intermediates, lacking the whole distal (PD) module (PubMed:33060577). Prevents the binding of the plant specific P1 protein (CPN60/HSP60), responsible for the linkage of the proximal (PP) to the distal (PD) module (PubMed:33060577)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR007173 ALO_C
IPR016166 FAD-bd_PCMH
IPR036318 FAD-bd_PCMH-like_sf
IPR016167 FAD-bd_PCMH_sub1
IPR016169 FAD-bd_PCMH_sub2
IPR010031 FAD_lactone_oxidase-like
IPR010029 GL_DH
IPR006094 Oxid_FAD_bind_N