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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 3-oxo-Delta(4,5)-steroid 5-beta-reductase

UniprotKB/SwissProt ID: Q9STX2 (Q9STX2)

Gene Name: VEP1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Involved in vascular strand development. Catalyzes the stereospecific conversion of progesterone to 5-beta-pregnane-3,20-dione. Can use progesterone, testosterone, 21-acetyl cortexone, 2-cyclohexenone, but-1-en-3-one, ethyl acrylate, ethylmethacrylate, cortisone and canarigenone as substrates, lower activity with 3-methyl-2-cyclohexenone and 3,5,5-trimethyl-2-cyclohexenone as substrate, and no activity with canarigenin, canarigenin digitoxoside and pregnenolone. May be involved in the formation of 5-beta phytoecdysteroids

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036291 NAD(P)-bd_dom_sf
IPR055222 PRISE-like_Rossmann-fold

The S-nitrosylation sites of Q9STX2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 116 WTNRESESEN C EANGSMLRNV   
2 275 DPYAKNEAFN C NNADIFKWKH   
3 80 NADHPIDYIQ C DVSDAEDTRS