UniprotKB/SwissProt ID: Q9SMT7 (Q9SMT7)
Gene Name:
AAE3
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Oxalyl-CoA synthetase acting exclusively against oxalate (PubMed:22447686, PubMed:27326693). Follows a two-step reaction mechanism, wherein oxalate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield oxalyl-CoA (By similarity). No activity with malonate, succinate, malate, acetate, formate, lactate, glycolate, glyoxylate or glutarate (PubMed:22447686). Required for oxalate degradation, normal seed development and defense against oxalate-producing fungal pathogens (PubMed:22447686)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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