UniprotKB/SwissProt ID: Q9SFU0 (Q9SFU0)
Gene Name:
SEC24A
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential protein (PubMed:19933202). Component of the coat protein complex II (COPII), that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus (PubMed:19933202, PubMed:24587212). COPII is composed of at least five proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1 (By similarity). Acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (PubMed:19933202). Involved in maintaining the dynamic identity of organelles of the early secretory pathway (PubMed:19933202). Regulates cell size patterning, and prevents CDKA;1-, DEK1- and ACR4-dependent endoreduplication and giant cells formation in sepals (PubMed:25315606). Required for male gametophytes (pollen grains) development and transmission (PubMed:21705385) (Microbial infection) Contributes to viral systemic infection of turnip mosaic virus (TuMV) by triggering the formation of host endoplasmic reticulum (ER)-derived viral vesicles that carry the viral RNA (vRNA) to plasmodesmata for cell-to-cell viral movement
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle, COPII-coated vesicle membrane. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm, cytosol
|
|
|
