Protein Name:
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
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UniprotKB/SwissProt ID: Q9R1J0 (Q9R1J0)
Gene Name:
Nsdhl
Organism: Mus musculus (Mouse)
Function: Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (PubMed:10369263, PubMed:14567972). Plays a role in the regulation of the endocytic trafficking of EGFR (PubMed:23125191)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Lipid droplet
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Graphical Visualization of S-nitrosylation Sites:
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