UniprotKB/SwissProt ID: Q9R0S3 (Q9R0S3)
Gene Name:
Mmp17
Organism: Mus musculus (Mouse)
Function: Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Secreted, extracellular space, extracellular matrix
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