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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytosolic Fe-S cluster assembly factor NUBP2

UniprotKB/SwissProt ID: Q9R061 (Q9R061)

Gene Name: Nubp2

Organism: Mus musculus (Mouse)

Function: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure (PubMed:23807208)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000808 Mrp-like_CS
IPR019591 Mrp/NBP35_ATP-bd
IPR028600 NUBP2/Cfd1_eukaryotes
IPR027417 P-loop_NTPase
IPR033756 YlxH/NBP35