Protein Name:
Glycine N-methyltransferase
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UniprotKB/SwissProt ID: Q9QXF8 (Q9QXF8)
Gene Name:
Gnmt
Organism: Mus musculus (Mouse)
Function: Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate (PubMed:15340920). Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine (PubMed:16779654)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9QXF8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
147 |
LGNSFAHLPD C KGDQSEHRLA |
CCCCEEHHHH H CCCCCCCCHH |
5.11% |
22178444
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| 2 |
186 |
RNYDYILSTG C APPGKNIYYK |
CCCCEEHHHH H CCCCCCCCHH |
5.35% |
22178444
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| 3 |
247 |
SKFRLSYYPH C LASFTELVRA |
CCCCEEHHHH H CCCCCCCCHH |
2.68% |
22178444
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