Protein Name:
2-hydroxyacyl-CoA lyase 1
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UniprotKB/SwissProt ID: Q9QXE0 (Q9QXE0)
Gene Name:
Hacl1
Organism: Mus musculus (Mouse)
Function: Peroxisomal 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner (By similarity). Involved in the degradation of 3-methyl-branched fatty acids like phytanic acid and the shortening of 2-hydroxy long-chain fatty acids (By similarity). Plays a significant role in the biosynthesis of heptadecanal in the liver (PubMed:29027957)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Peroxisome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9QXE0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
243 |
EDSIRKLVEQ C SLPFLPTPMG |
CCCCCCCCCC C CCHHHHHHHH |
2.6% |
22178444
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| 2 |
264 |
KGVVPDNHPN C VGAARSRALQ |
CCCCCCCCCC C CCHHHHHHHH |
3.35% |
22178444
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| 3 |
415 |
MDIGRTMLQN C LPRHRLDAGS |
CCCCCCCCCC C CCHHHHHHHH |
3.4% |
22178444
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