Protein Name:
Deoxyguanosine kinase, mitochondrial
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UniprotKB/SwissProt ID: Q9QX60 (Q9QX60)
Gene Name:
Dguok
Organism: Mus musculus (Mouse)
Function: Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine (PubMed:10455141). In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs (PubMed:10455141). Widely used as target of antiviral and chemotherapeutic agents
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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