Protein Name:
Proteasome subunit alpha type-6
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UniprotKB/SwissProt ID: Q9QUM9 (Q9QUM9)
Gene Name:
Psma6
Organism: Mus musculus (Mouse)
Function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9QUM9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
154 |
DEEQGPQVYK C DPAGYYCGFK |
CCCCCCCCCC C EEEEECCCCC |
4.08% |
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| 2 |
161 |
VYKCDPAGYY C GFKATAAGVK |
CCCCCCCCCC C EEEEECCCCC |
3.78% |
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| 3 |
47 |
LTSVAVRGKD C AVIVTQKKVP |
CCCCCCCCCC C EEEEECCCCC |
3.57% |
20925432
21278135
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| 4 |
78 |
HLFKITESIG C VMTGMTADSR |
CCCCCCCCCC C EEEEECCCCC |
1.48% |
21278135
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