Protein Name:
Long-chain-fatty-acid--CoA ligase 4
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UniprotKB/SwissProt ID: Q9QUJ7 (Q9QUJ7)
Gene Name:
Acsl4
Organism: Mus musculus (Mouse)
Function: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane. Peroxisome membrane. Microsome membrane. Endoplasmic reticulum membrane. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9QUJ7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
157 |
LKPKNTIAIF C ETRAEWMIAA |
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| 2 |
494 |
TTGRVGAPLI C CEIKLKDWQE |
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| 3 |
595 |
LGKVEAALKN C PLIDNICAFA |
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| 4 |
602 |
LKNCPLIDNI C AFAKSDQSYV |
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