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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cleavage and polyadenylation specificity factor subunit 2

UniprotKB/SwissProt ID: Q9P2I0 (Q9P2I0)

Gene Name: CPSF2

Organism: Homo sapiens (Human)

Function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR022712 Beta_Casp
IPR027075 CPSF2
IPR025069 Cpsf2_C
IPR035639 CPSF2_MBL
IPR001279 Metallo-B-lactamas
IPR036866 RibonucZ/Hydroxyglut_hydro
IPR011108 RMMBL

The S-nitrosylation sites of Q9P2I0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 335 VVLASQPDLE C GFSRDLFIQW   
2 522 DQDLSDVPTK C ISTTESIEIK