Protein Name:
NFX1-type zinc finger-containing protein 1
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UniprotKB/SwissProt ID: Q9P2E3 (Q9P2E3)
Gene Name:
ZNFX1
Organism: Homo sapiens (Human)
Function: RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses (PubMed:33872655). Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response (By similarity). Also required for immunity against some bacteria, such as mycobacteria (PubMed:33876776)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane. Cytoplasm, Stress granule
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Graphical Visualization of S-nitrosylation Sites:
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