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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NCK-interacting protein with SH3 domain

UniprotKB/SwissProt ID: Q9NZQ3 (Q9NZQ3)

Gene Name: NCKIPSD

Organism: Homo sapiens (Human)

Function: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR030125 SPIN90/Ldb17
IPR018556 SPIN90/Ldb17_LRD
IPR035514 SPIN90_SH3

The S-nitrosylation sites of Q9NZQ3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 700 ILNEEETSPQ C QMDRMIVREM