Protein Name:
Rho guanine nucleotide exchange factor 12
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UniprotKB/SwissProt ID: Q9NZN5 (Q9NZN5)
Gene Name:
ARHGEF12
Organism: Homo sapiens (Human)
Function: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9NZN5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1325 |
FRTGTGDIAT C YSPRTSTESF |
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| 2 |
294 |
DPGDVLGRTD C SSGDASRPSS |
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| 3 |
726 |
PPLDQVQEEE C EVERVTEHGT |
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| 4 |
921 |
FVQDAESNPL C RRLQLKDIIP |
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