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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ubiquitin-associated protein 1

UniprotKB/SwissProt ID: Q9NZ09 (Q9NZ09)

Gene Name: UBAP1

Organism: Homo sapiens (Human)

Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process (PubMed:21757351, PubMed:22405001, PubMed:31203368). Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) (PubMed:21757351, PubMed:22405001). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2 (PubMed:22405001, PubMed:24284069, PubMed:31203368)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Endosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015940 UBA
IPR009060 UBA-like_sf
IPR049467 UBAP-1-like_UBA2
IPR038870 UBAP1
IPR042575 UBAP1_C
IPR023340 UMA

The S-nitrosylation sites of Q9NZ09

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 161 KADFNLADFE C EEDPFDNLEL