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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: U3 small nucleolar RNA-associated protein 6 homolog

UniprotKB/SwissProt ID: Q9NYH9 (Q9NYH9)

Gene Name: UTP6

Organism: Homo sapiens (Human)

Function: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003107 HAT
IPR011990 TPR-like_helical_dom_sf
IPR013949 Utp6
IPR056907 UTP6_C
IPR055347 UTP6_N

The S-nitrosylation sites of Q9NYH9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 370 KAHELKLLSE C QYKQLSVSLL   
2 524 MIQFEKEQES C NMANIREYYE