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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ras-related protein Rab-20

UniprotKB/SwissProt ID: Q9NX57 (Q9NX57)

Gene Name: RAB20

Organism: Homo sapiens (Human)

Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB20 plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR041836 Rab20
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase

The S-nitrosylation sites of Q9NX57

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 106 LGLTDTASKD C LFAIVGNKVD   
2 131 GALAGQEKEE C SPNMDAGDRV   
3 179 EQDVPAAEQM C FETSAKTGYN