Protein Name:
E3 ubiquitin-protein ligase MARCHF5
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UniprotKB/SwissProt ID: Q9NX47 (Q9NX47)
Gene Name:
MARCHF5
Organism: Homo sapiens (Human)
Function: Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion outer membrane. Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9NX47
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
33 |
DDRTAEWVRP C RCRGSTKWVH |
CCHHHHHHHH H HCCEEEEEEC |
4.49% |
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| 2 |
46 |
RGSTKWVHQA C LQRWVDEKQR |
CCHHHHHHHH H HCCEEEEEEC |
2.4% |
21278135
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