Protein Name:
PIH1 domain-containing protein 1
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UniprotKB/SwissProt ID: Q9NWS0 (Q9NWS0)
Gene Name:
PIH1D1
Organism: Homo sapiens (Human)
Function: Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9NWS0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
117 |
HAELDAKGQG C TAYDVAVNSD |
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| 2 |
55 |
STQIQPQPGF C IKTNSSEGKV |
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