Protein Name:
Pre-mRNA-splicing factor RBM22
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UniprotKB/SwissProt ID: Q9NW64 (Q9NW64)
Gene Name:
RBM22
Organism: Homo sapiens (Human)
Function: Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28076346, PubMed:28502770, PubMed:29301961, PubMed:29360106, PubMed:29361316, PubMed:30705154). Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9NW64
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
179 |
VKGECKRGEE C PYRHEKPTDP |
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| 2 |
24 |
NWEDADFPIL C QTCLGENPYI |
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| 3 |
269 |
RTITVVQRQQ C AFIQFATRQA |
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| 4 |
71 |
VRMRFKKTEV C QTCSKLKNVC |
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