Protein Name:
Poly(A) RNA polymerase, mitochondrial
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UniprotKB/SwissProt ID: Q9NVV4 (Q9NVV4)
Gene Name:
MTPAP
Organism: Homo sapiens (Human)
Function: Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9NVV4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
242 |
SSVNTFGKLG C DLDMFLDLDE |
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| 2 |
324 |
RFSHQASGFQ C DLTTNNRIAL |
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| 3 |
412 |
LKTLADAEDK C VIEGNNCTFV |
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| 4 |
419 |
EDKCVIEGNN C TFVRDLSRIK |
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| 5 |
82 |
EQAQRTVLIH C PEKISENKFL |
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