Protein Name:
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1
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UniprotKB/SwissProt ID: Q9NV66 (Q9NV66)
Gene Name:
TYW1
Organism: Homo sapiens (Human)
Function: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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