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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: U3 small nucleolar ribonucleoprotein protein IMP3

UniprotKB/SwissProt ID: Q9NV31 (Q9NV31)

Gene Name: IMP3

Organism: Homo sapiens (Human)

Function: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR022801 Ribosomal_uS4
IPR001912 Ribosomal_uS4_N
IPR002942 S4_RNA-bd
IPR036986 S4_RNA-bd_sf

The S-nitrosylation sites of Q9NV31

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 107 LCDFVTASSF C RRRLPTVLLK