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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Structural maintenance of chromosomes protein 4

UniprotKB/SwissProt ID: Q9NTJ3 (Q9NTJ3)

Gene Name: SMC4

Organism: Homo sapiens (Human)

Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
IPR024704 SMC
IPR010935 SMC_hinge
IPR036277 SMC_hinge_sf

The S-nitrosylation sites of Q9NTJ3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1288 NPKEIASKGL C ----------   
2 158 NSDEHKDIQS C TVEVHFQKII   
3 190 NSNFYVSRTA C RDNTSVYHIS   
4 260 MLEYLEDIIG C GRLNEPIKVL   
5 916 LDKINKQLDE C ASAITKAQVA