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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Isoleucine--tRNA ligase, mitochondrial
UniprotKB/SwissProt ID: Q9NSE4 (Q9NSE4)

Gene Name: IARS2

Organism: Homo sapiens (Human)

Function: Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile))

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001412 aa-tRNA-synth_I_CS
IPR002300 aa-tRNA-synth_Ia
IPR033708 Anticodon_Ile_BEm
IPR002301 Ile-tRNA-ligase
IPR023585 Ile-tRNA-ligase_type1
IPR050081 Ile-tRNA_ligase
IPR013155 M/V/L/I-tRNA-synth_anticd-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR009008 Val/Leu/Ile-tRNA-synth_edit
IPR010663 Znf_FPG/IleRS
The S-nitrosylation sites of Q9NSE4
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1002 KYTAESSDTL C PRCAEVVSGK   
2 1005 AESSDTLCPR C AEVVSGK---   
3 155 SKIHFVPGWD C HGLPIEIKVL   
4 819 EKENDPKRRS C QTALVEILDV   
5 91 PDTELEIQQK C GFSELYSWQR