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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Lymphoid-specific helicase

UniprotKB/SwissProt ID: Q9NRZ9 (Q9NRZ9)

Gene Name: HELLS

Organism: Homo sapiens (Human)

Function: Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C-like
IPR044753 HELLS_N
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR049730 SNF2/RAD54-like_C
IPR000330 SNF2_N

The S-nitrosylation sites of Q9NRZ9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 169 EDENSSSTNL C VEDLQKNKDS   
2 836 LENSEDSSPE C LF--------